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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
9 DPC

8 matching records from 8 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Spry2  sprouty RTK signaling antagonist 2   (Synonyms: sprouty2)
Results  Reference
1J:131764 Basson MA, Echevarria D, Petersen Ahn C, Sudarov A, Joyner AL, Mason IJ, Martinez S, Martin GR, Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development. Development. 2008 Mar;135(5):889-98
1*J:83255 Chi CL, Martinez S, Wurst W, Martin GR, The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development. 2003 Jun;130(12):2633-44
1*J:116164 Dequeant ML, Glynn E, Gaudenz K, Wahl M, Chen J, Mushegian A, Pourquie O, A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science. 2006 Dec 8;314(5805):1595-8
1J:156717 Guo Q, Li K, Sunmonu NA, Li JY, Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum. Dev Biol. 2010 Feb 15;338(2):183-92
1J:276709 Hashimoto K, Yamaguchi Y, Kishi Y, Kikko Y, Takasaki K, Maeda Y, Matsumoto Y, Oka M, Miura M, Ohata S, Katada T, Kontani K, Loss of the small GTPase Arl8b results in abnormal development of the roof plate in mouse embryos. Genes Cells. 2019 Jun;24(6):436-448
1J:97106 Lin W, Jing N, Basson MA, Dierich A, Licht J, Ang SL, Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region. Genesis. 2005 Mar;41(3):110-5
1J:176602 Simrick S, Lickert H, Basson MA, Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo. Dev Biol. 2011 Oct 1;358(1):147-55
1*J:185606 Simrick S, Szumska D, Gardiner JR, Jones K, Sagar K, Morrow B, Bhattacharya S, Basson MA, Biallelic expression of Tbx1 protects the embryo from developmental defects caused by increased receptor tyrosine kinase signaling. Dev Dyn. 2012 Aug;241(8):1310-24

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory